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  • Home
  • Research
  • Publications
  • About Ross (PI)
  • Members
  • Outreach
  • Resources and Lab Equipment
  • Patents
  • Teaching
  • Positions Available
  • Contact
  • Lab Pictures

Publications

Journal Publications
 "*": Corresponding Author; "+": Equal Contribution;  Undergraduate Contributions are underlined.

At Temple University
37. Benjamin L. Prather+, Shuyue Ji+, Yue Zhao, Femil Joseph Shajan, Mi Zhao, Zakey Yusuf Buuh, Robert Maloney, Rui Zhang, Carson Cohen, Rongsheng E. Wang*, "Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity", Acta Pharmaceutica Sinica B, 2022,  ASAP,  doi: 10.1016/j.apsb.2022.08.003  
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36. Carson Cohen+, Todd R. Lewis+, Rongsheng E. Wang*, "The role of post-translational modifications in cancer",  Handbook of Cancer and Immunology. 2022, Springer, Cham. doi: 10.1007/978-3-030-80962-1_288-1
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35. Md Shafiqul Islam, Samuel L. Junod, Si Zhang, Zakey Yusuf Buuh, Yifu Guan, Mi Zhao, Kishan H. Kaneria, Parmila Kafley, Carson Cohen, Robert Maloney, Zhigang Lyu, Vincent A. Voelz, Weidong Yang, Rongsheng E. Wang*, "Unprotected peptide macrocyclization and stapling via a fluorine-thiol displacement reaction", Nature Communications, 2022, 13, 350. doi: 10.1038/s41467-022-27995-5 
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34. Tiantian Li, Yuhan Zhang, Xiangqian Jia, Yanchao Ding, Mengling Wu, Luyao Wang, Hang Chen, Rui Zhu, Rongsheng E. Wang, Chenjun Shen, Feng Wang, Juanjuan Du*, "Rational design of bispecific antibody drug conjugates with balanced potency and selectivity", , submitted.
33. Jinfeng Kang, Todd R. Lewis, Alexander C. Gardner, Rodrigo B. Andrade, Rongsheng E. Wang*, "Semi-Syntheses and Interrogation of Indole-Substituted Aspidosperma Terpenoid Alkaloids", Organic & Biomolecular Chemistry, 2022, 20, 3988-3997.
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32. Zhigang Lyu, Yue Zhao, Zakey Yusuf Buuh, Nicole Gorman, Aaron R Goldman, Md Shafiqul Islam, Hsin-Yao Tang, Rongsheng E. Wang*, "Steric-free bioorthogonal labeling of acetylation substrates based on a fluorine-thiol displacement reaction (FTDR)", Journal of the American Chemical Society, 2021, 143: 3, 1341-1347.  doi: 10.1021/jacs.0c05605
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Highlighted by Faculty Opinions/F1000. [Link] 
Highlighted by ScienceNet. [Link]
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Highlighted by X-Mol. [Link]
31. Robert Maloney+, Zakey Yusuf Buuh+, Yue Zhao+, Rongsheng E. Wang*, "Site-specific antibody fragment conjugates for targeted imaging",  Methods in Enzymology, 2020, 638: 295-320. doi: 10.1016/bs.mie.2020.02.023
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30. Yuhan Zhang , Changming Fang , Rongsheng E. Wang , Ying Wang , Hui Guo , Chao Guo , Lijun Zhao , Shuhong Li , Xia Li , Peter G. Schultz*, Yu Joshua Cao , Feng Wang, "A tumor-targeted immune checkpoint blocker",  Proceedings of the National Academy of Sciences U S A, 2019, 116(32):15889-15894. doi: 10.1073/pnas.1905646116.
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29. Haley L. Wissler+, Emily B. Ehlerding+, Zhigang Lyu, Yue Zhao, Si Zhang, Anisa Eshraghi, Zakey Yusuf Buuh, Jeffrey C. McGuth, Yifu Guan, Jonahan W. Engle, Sarah J. Bartlett, Vincent A. Voelz, Weibo Cai, Rongsheng E. Wang*, "A site-specific immunoPET tracer to image PD-L1", Molecular Pharmaceutics, 2019, 16(5):2028-2036. doi: 10.1021/acs.molpharmaceut.9b00010.
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28. Zhigang Lyu+, Lei Kang+, Zakey Yusuf Buuh, Dawei Jiang, Jeffrey McGuth, Juanjuan Du, Haley L. Wissler, Weibo Cai, Rongsheng E. Wang*, “A switchable site-specific antibody conjugate”,  ACS Chemical Biology, 2018, 13(4):958-964. doi: 10.1021/acschembio.8b00107.
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27. Zakey Yusuf Buuh, Zhigang Lyu, Rongsheng E. Wang*, “Interrogating the roles of post-translational modifications of non-histone proteins”, Journal of Medicinal Chemistry, 2017, 61(8):3239-3252. doi: 10.1021/acs.jmedchem.6b01817.
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26. Xiaozhou Luo, Guangsen Fu, Rongsheng E. Wang, Xueyong Zhu, Claudio Zambaldo, Renhe    Liu, Tao Liu, Xiaoxuan Lyu, Jintang Du, Weimin Xuan, Anzhi Yao, Sean A. Reed, Mingchao Kang, Yuhan Zhang, Hui Guo, Chunhui Huang, Peng-Yu Yang, Ian A. Wilson, Peter G. Schultz*, and Feng Wang*, “Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria”, Nature Chemical Biology, 2017, 13(8):845-849. doi: 10.1038/nchembio.2405.
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Before Temple University
25. Rongsheng E. Wang, Ying Wang, Yuhan Zhang, Chase Gabrelow, Yong Zhang, Victor Chi, Qiangwei Fu, Xiaozhou Luo, Danling Wang, Sean Joseph, Kristen Johnson, Arnab Chatterjee, Timothy M. Wright, Van Nguyen-Tran, John Tejaro, Argyrios N. Theofilopoulos, Peter G. Schultz*, and Feng Wang*, “Rational design of a Kv1.3 channel blocking antibody as a selective immunosuppressant”, Proceedings of the National Academy of Sciences U S A., 2016, doi: 10.1073/pnas.1612803113
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24. Xiaozhou Luo, Claudio Zambaldo, Tao Liu, Yuhan Zhang, Weimin Xuan, Chen Wang, Sean   A. Reed, Peng-yu Yang, Rongsheng E. Wang, Tsotne Javahishvili, Peter G. Schultz*, and Travis S. Young*, “Recombinant thiopeptides containing noncanonical amino acids”, Proceedings of the National Academy of Sciences U S A., 2016, 113(13): 3615-3620

23. Renhe Liu, Rongsheng E. Wang, Feng Wang*, “Antibody-Drug Conjugates for Non-oncological Indications”,  Expert Opinion on Biological Therapy, 2016, 16 (5): 591-593

22. Xiaozhou Luo, Tao Liu, Ying Wang, Haiqun Jia, Yuhan Zhang, Dawna Caballero, Juanjuan Du, Rongsheng E. Wang, Danling Wang, Peter G. Schultz* and Feng Wang*, “An Epitope-Specific Respiratory Syncytial Virus Vaccine based on an Antibody Scaffold”, Angewandte Chemie International Edition, 2015, 54 (48): 14531-14534

21. Rongsheng E. Wang+, Tao Liu+, Ying Wang, Yu Cao, Jintang Du, Xiaozhou Luo, Vishal Deshmukh, Chan Hyuk Kim, Brian R. Lawson, Matthew S. Tremblay, Travis S. Young, Stephanie A. Kazane*, Feng Wang*, Peter G. Schultz*, “An Immunosuppressive Antibody-Drug Conjugate”, Journal of The American Chemical Society, 2015, 137 (9): 3229–3232  
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20. Yu Cao, Jun Y. Axup,Jennifer S. Y. Ma, Rongsheng E. Wang, Seihyun Choi, Virginie Tardif, Reyna K. V. Lim, Holly M. Pugh, Brian R. Lawson, Gus Welzel, Stephanie A. Kazane, Ying Sun, Feng Tian, Shailaja Srinagesh, Tsotne Javahishvili, Peter G. Schultz*, Chan Hyuk Kim*, “Multiformat T-Cell-Engaging Bispecific Antibodies Targeting Human Breast Cancers”,  Angewandte Chemie International Edition, 2015, 54(24):7022-7027       
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19. Tao Liu, Guangsen Fu, Xiaozhou Luo, Yan Liu, Ying Wang, Rongsheng E. Wang, Peter G. Schultz *, Feng Wang*, “Rational Design of Antibody Protease Inhibitors”,  Journal of The American Chemical Society, 2015, 137(12): 4042-4045     
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18. Rongsheng E. Wang*, Yin Zhang, Ling Tian, Weibo Cai, Jianfeng Cai,  “Antibody-based Imaging of HER-2: Moving into the Clinic”, Current Molecular Medicine, 2013, 13(10): 1523-1537

17. Rongsheng E. Wang+, Ling Tian+, Yie-Hwa Chang*, “A Homogeneous Fluorescent Sensor for Human Serum Albumin”, Journal of Pharmaceutical and Biomedical Analysis, 2012, 63: 165-169
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16. Ling Tian+, Rongsheng E. Wang+, Ying Fei, Yie-Hwa Chang*, “A Homogeneous Fluorescent Assay for cAMP-Phosphodiesterase Enzyme Activity”, Journal of Biomolecular Screening, 2012, 17(3): 409-414
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15. Ling Tian, Rongsheng E. Wang, Yie-Hwa Chang*,  “Molecular PINCERs for Biomarker Analysis and Their Potential Application in HCV Diagnosis”, Antiviral Therapy, 2012, 17(7 Pt B): 1437-1442

14. Rongsheng E. Wang*, Frankie Costanza, Youhong Niu, Haifan Wu, Yaogang Hu, Whitney Hang, Yiqun Sun, Jianfeng Cai*, “Development of Self-Immolative Dendrimers for Drug Delivery and Sensing”, Journal of Controlled Release, 2012, 159(2): 154-163
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13. Haifan Wu, Youhong Niu, Shruti Padhee, Rongsheng E. Wang, Yaqiong Li, Qiao Qiao, Ge Bai, Chuanhai Cao, Jianfeng Cai*, “Design and Synthesis of Unprecedented Cyclic γ-AApeptides for Antimicrobial Development”, Chemical Science, 2012, 3(8): 2570-2575
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12. Rongsheng E. Wang, Youhong Niu, Haifan Wu, Yaogang Hu, Jianfeng Cai*, “Development of NGR-Based Anti-Cancer Agents for Targeted Therapeutics and Imaging”, Anticancer Agents in Medicinal Chemistry, 2012, 12(1): 76-86 

11. Ge Bai, Shruti Padhee, Youhong Niu, Rongsheng E. Wang, Qiao Qiao, Robert Buzzeo, Chuanhai Cao*, Jianfeng Cai*, “Cellular Uptake of an α-AApeptide”, Organic and Biomolecular Chemistry, 2012, 10(6): 1149-1153

10. Youhong Niu+, Rongsheng E. Wang+,* Haifan Wu,a Jianfeng Cai,* “Recent development of small antimicrobial peptidomimetics, Future Medicinal Chemistry, 2012, 4(14): 1853-1862

9.  Youhong Niu, Ge Bai, Haifan Wu, Rongsheng E. Wang, Qiao Qiao, Shruti Padhee, Robert Buzzeo, Chuanhai Cao*, Jianfeng Cai*, “Cellular Translocation of a γ-AApeptide Mimetic of Tat Peptide”, Molecular Pharmaceutics, 2012, 9(5): 1529-1534
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8.  Yaogang Hu, Mohamad Nassir Amin, Shruti Padhee, Rongsheng E. Wang, Archana Mattew, Jianfeng Cai*, “Lipidated α-AApeptides With Improved Antimicrobial Activity”, ACS Medicinal Chemistry Letter, 2012, 3(8): 683-686
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7.  Rongsheng E. Wang, Raj K. Pandita, Jianfeng Cai, Clayton R. Hunt, John Stephen Taylor*, “Inhibition of Heat Shock Transcription Factor Binding by a Linear Polyamide Binding in an unusual 1:1 Mode”, ChemBioChem, 2012, 13(1): 97-104
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6.  Rongsheng E. Wang, Youhong Niu, Haifan Wu, Mohamad Nassir Amin, Jianfeng Cai*, “Development of NGR Peptide-Based Agents for Tumor Imaging”, American Journal of Nuclear Medicine and Molecular Imaging, 2011, 1(1): 36-46 

5.  Rongsheng E. Wang, Yin Zhang, Jianfeng Cai, Weibo Cai, Ting Gao*, “Aptamer-Based Fluorescent Biosensors”, Current Medicinal Chemistry, 2011, 18(27): 4175-4184 

4.  Rongsheng E. Wang, Clayton R. Hunt, Jiawei Chen, John-Stephen Taylor*, “Biotinylated Quercetin as an Intrinsic Photoaffinity Proteomics Probe for the Identification of Quercetin Target Proteins”, Bioorganic and Medicinal Chemistry, 2011, 19(16): 4710-20
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3.  Rongsheng E. Wang*, Haifan Wu, Youhong Niu, Jianfeng Cai*, “Improving the Stability of Aptamers by Chemical Modification”, Current Medicinal Chemistry, 2011, 18(27): 4126-4138 

2.  Rongsheng E. Wang*, “Targeting Heat Shock Proteins 70/90 and Proteasome for Cancer Therapy”, Current Medicinal Chemistry, 2011,  18(27): 4250-4264
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1.  Rongsheng E. Wang, Jeffrey L.-F. Kao, Carolyn A. Hilliard, Raj K. Pandita, Joseph L. Roti Roti, Clayton R. Hunt, John-Stephen Taylor*, “Inhibition of Heat Shock Induction of Heat Shock Protein 70 and Enhancement of Heat Shock Protein 27 Phosphorylation by Quercetin  Derivatives”, Journal of Medicinal Chemistry, 2009, 52(7): 1912-21
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Book Chapters
 "*": Corresponding Author; "+": Equal Contribution

1.
Youhong Niu+, Yaogang Hu+, Rongsheng E. Wang+, Xiaolong Li+, Haifan Wu, Jiandong Chen, Jianfeng Cai, “AApeptides as a New Class of Peptidomimetics to Regulate Protein-Protein Interactions”, protein interaction / Book 1, InTech press, (edited by Jianfeng Cai and Rongsheng E Wang)
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