Department of Chemistry, College of Science and Technology,
Temple University
Affiliations: Fox Chase Cancer Center, Lewis Katz School of Medicine;
Temple University
Center for Targeted Therapeutics & Translational Nanomedicine,
University of Pennsylvania
Chemical Biology
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08/2024 - Lab summer party in front of the Philadelphia Art Museum to celebrate the newly minted Ph.D. graduates - Dr. Jinfeng Kang and Dr. Yue Zhao.
10/2023 - Congratulations to Hailey Lightle, Parmila Kafley, and Todd Lewis on publishing a paper on METHODS.
10/2023 - Our graduate student Parmila Kafley has been highlighted by the National Institutes of Health / NIGMS. Her interview can be checked out here.
08/2023 - Ross is selected as a American Chemical Society (ACS) MEDI Division Young Investigator
06/2023 - Ross is officially tenured and promoted to Associate Professor.
04/2023 - Shafiq successfully defended his Ph.D. thesis and is working now at Charles River Laboratories.
12/2022 - We would like to extend our warmest welcome to the new 1st-year graduate students who recently joined our lab: Hailey
Lightle, Radhesh Agarwal, and Benjamin Prather. Welcome aboard, Class of 2022 !!
Lightle, Radhesh Agarwal, and Benjamin Prather. Welcome aboard, Class of 2022 !!
11/2022 - Ross has received the Rising Star/Young Chemical Biologist Award from the International Chemical Biology Society!
08/2022 - Congratulations to Parmila Kafley for receiving a NIH Diversity Supplement Award, which will fund her research on T cell
receptor mediated immunomodulation.
receptor mediated immunomodulation.
08/2022 - Ross joins the ADC Discovery Network and is invited to serve as a strategic scientific advisor.
07/2022 - Congratulations to Benjamin Prather, Shuyue Ji, et al. for publishing the acetaminophen (Tylenol) mechanism studies in Acta
Pharmaceutica Sinica B.
Pharmaceutica Sinica B.
06/2022 - Congratulations to Carson Cohen and Todd Lewis for having their review paper "The role of post-translational modifications
in cancer" accepted for publication in the Handbook of Cancer and Immunology.
in cancer" accepted for publication in the Handbook of Cancer and Immunology.
04/2022 - Congratulations to Jinfeng, Todd, and our collaborators Alex and Dr. Rod Andrade for publishing the tabersonine semi-
synthesis and medicinal chemistry activity studies at Organic & Biomolecular Chemistry! This article is also in deep memory
of our beloved Dr. Rod Andrade!
synthesis and medicinal chemistry activity studies at Organic & Biomolecular Chemistry! This article is also in deep memory
of our beloved Dr. Rod Andrade!
03/2022 - Congratulations to Dr. Zhigang Lyu on starting his new position as a senior scientist at Bristol Myers Squibb (BMS)!
01/2022 - Congratulations to Shafiqul, Zakey, Yifu, Mi, et al., and our collaborator teams Si/Dr. Vince Voelz and Sam/Dr. Weidong Yang
for publishing our fluorine-thiol displacement based peptide stapling platform at Nature Communications!
for publishing our fluorine-thiol displacement based peptide stapling platform at Nature Communications!
01/2022 - The lab has received the Catalytic Collaborative Funding Initiative (the CAT Program) to support our research on neuron-
regenerative peptides. We thank the University OVPR for the support!
regenerative peptides. We thank the University OVPR for the support!
12/2021 - Ross has received the Dean's Distinguished Teaching Award!
12/2021 - With this Chemical Machinery of the Cell Collaborative Innovation Award, we look forward to working with Professor Stephen
Fried @ Johns Hopkins University and Professor W. Seth Childers @ University of Pittsburgh!
Fried @ Johns Hopkins University and Professor W. Seth Childers @ University of Pittsburgh!
12/2021 - The lab has received a 5-year NSF CAREER Award to support our medicinal chemistry and cell biology studies aimed at
understanding the intra-cellular activities of post-translational modification enzymes.
understanding the intra-cellular activities of post-translational modification enzymes.
11/2021 - Congratulations to the lab's graduate student, Md Shafiqul Islam, on winning the Daniel Swern Research Award!
09/2021 - The lab has received a P30 pilot grant from NIDA and Temple Univ Center for Substance Abuse, which will allow us to exploit
the FTDR chemical labeling approach to study the toxicity mechanism of abused pain relievers such as Tylenol and Opioids.
the FTDR chemical labeling approach to study the toxicity mechanism of abused pain relievers such as Tylenol and Opioids.
07/2021 - The lab's first two Ph.D. students have both successfully defended! Congratulations to Dr. Zakey Buuh and Dr. Zhigang Lyu.
Can't wait to see the amazing ways you continue to transform research and education. Best of luck at TCIS and Frontage!
Can't wait to see the amazing ways you continue to transform research and education. Best of luck at TCIS and Frontage!
05/2021 - The lab has participated in the virtual 13th Annual Frontiers in Chemistry and Biology Interface Symposium (FCBIS) hosted by
University of Maryland, with multiple group members (Rob, Shuyue, Yue) presenting their research. Zhigang was also invited
to orally present our invention of the FTDR chemical reaction for profiling cellular acetylation.
University of Maryland, with multiple group members (Rob, Shuyue, Yue) presenting their research. Zhigang was also invited
to orally present our invention of the FTDR chemical reaction for profiling cellular acetylation.
01/2021 - Ross was highlighted in Fox Chase Cancer Center Annual Report 2020 - "Five Up-And-Coming Faculty On the Cutting Edge"
12/2020 - Congratulations to Zhigang, Zakey, Yue, et al. and our mass spec collaborator Dr. Hsin-Yao Tang's team for publication of our
invention of the bioorthogonal FTDR reaction and its application to probing cellular acetylation in Journal of the American
Chemical Society!
invention of the bioorthogonal FTDR reaction and its application to probing cellular acetylation in Journal of the American
Chemical Society!
12/2020 - We would like to officially welcome our three newest graduate students: Carson Cohen, Parmila Kafley, and Todd Lewis.
Welcome aboard, Class of 2020 !!
Welcome aboard, Class of 2020 !!
06/2020 - Congratulations to Robert Maloney for passing all the required cumulative examinations and becoming an official Ph.D.
candidate before his first summer at Temple. That was quick !
candidate before his first summer at Temple. That was quick !
04/2020 - Congratulations to our first year student Robert Maloney for a first-authored publication in Methods in Enzymology !
01/2020 - We would like to extend our warm welcome to the postdoctoral researchers Dr. Kevin Zhang, and Dr. Mi Zhao.
12/2019 - We would like to officially welcome our two newest graduate students: Robert Maloney, and Shuyue Ji. Welcome aboard,
Class of 2019 !!
Class of 2019 !!
10/2019 - Ross's Scialog team proposal with Alison Ondrus (Caltech) and Abhishek Singharoy (ASU) has been selected for funding by
the Gordon and Betty Moore Foundation. It was a great conference at Scialog, and we look forward to exploring some cool
mechanochemical probes to study the force of life.
the Gordon and Betty Moore Foundation. It was a great conference at Scialog, and we look forward to exploring some cool
mechanochemical probes to study the force of life.
07/2019 - Ross has been named a Scialog Fellow of the Research Corporation for Scientific Advancement & the Gordon and Betty Moore Foundation.
06/2019 - The lab has received the 5-year Maximizing Investigator's Research Award (MIRA) from NIGMS. We thank the support from NIH. (CST highlights here)
06/2019 - The Wang Lab extends a warm welcome to NSF-REU student Deanna Wyche for summer research with us.
05/2019 - Congratulations to our undergrad Kaitlyn Halleran for receiving this year's Frances Velay Fellowship!
03/2019 - Haley, Emily, Zhigang, and Yue's research paper on 'A Site-Specific ImmunoPET Tracer to Image PD-L1" has been accepted for
publication in Molecular Pharmaceutics ! Congratulations to everyone and our collaborator Dr. Weibo Cai's team.
publication in Molecular Pharmaceutics ! Congratulations to everyone and our collaborator Dr. Weibo Cai's team.
1/2019 - Ross has been awarded a Leukemia SPORE Career Enhancement Award. We are thankful to the support from MD Anderson
Cancer Center (The University of Texas).
Cancer Center (The University of Texas).
10/2018 - Our Application Note on switchable antibody conjugation has been selected as the BUCHI Scholar Award Finalist. Check out
the linkage here .
10/2018 - Anisa presented our work on imaging immune checkpoint proteins at the South Atlantic Medical Scientist Annual Meeting.
Thanks to the Frances Velay Fellowship support for undergraduate summer research.
Thanks to the Frances Velay Fellowship support for undergraduate summer research.
05/2018 - Congratulations to Anisa Rose Eshraghi for receiving the Frances Velay Fellowship!
02/2018 - Zhigang, Lei and Zakey's research paper on 'A Switchable Site-Specific Antibody Conjugate' has been accepted for publication
in ACS Chemical Biology! (DOI: 10.1021/acschembio.8b00107) Congratulations to everyone and our collaborator Dr. Weibo
Cai's team, on a job well done!!
in ACS Chemical Biology! (DOI: 10.1021/acschembio.8b00107) Congratulations to everyone and our collaborator Dr. Weibo
Cai's team, on a job well done!!
01/2018 - Ross has been invited to serve on the University Award Selection Committee.
12/2017 - New funding !! - our lab has been awarded the ACS IRG grant. We are greatly thankful to the American Cancer Society and
the support from Fox Chase Cancer Center !
the support from Fox Chase Cancer Center !
12/2017 - The lab is excited to welcome three new graduate students to the group: Christopher Cherkis, Yue Zhao, and Md Shafiqul
Islam. Welcome aboard, Class of 2017 !!
Islam. Welcome aboard, Class of 2017 !!
10/2017 - Congratulations to Zakey and Zhigang for publishing our paper in the Journal of Medicinal Chemistry.
(DOI: 10.1021/acs.jmedchem.6b01817)
(DOI: 10.1021/acs.jmedchem.6b01817)
09/2017 - The lab welcomes undergrad students Elena Gonzalez and Jose Olivencia, who joined us through URP research program.
05/2017 - We are funded !! - our lab has received a grant from Fox Chase Cancer Center as the P30 award under the National Cancer
Institute of the NIH. We are excited for this opportunity and are thankful to FCCC and NCI for their support !
Institute of the NIH. We are excited for this opportunity and are thankful to FCCC and NCI for their support !
05/2017 - Ross has received a Summer Research Award from Temple CST.
05/2017 - Congratulations to Jeff McGuth on receiving the Creative Arts, Research And Scholarship (CARAS) grant !
05/2017- The lab welcomes undergrad student Jeffrey McGuth and also congratulates Haley Wissler for winning the Merit Scholarship !
04/2017 - Congratulations to Zakey for receiving the 2017 FSRI award !
04/2017 - Our co-authored paper "Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria" has been
published at Nature Chemical Biology (doi:10.1038/nchembio.2405)
published at Nature Chemical Biology (doi:10.1038/nchembio.2405)
03/2017 - The lab welcomes Adrien Schutz, who is an undergraduate student at University of Toulouse, France, and will stay with us for
his spring semester internship !
his spring semester internship !
02/2017 - The lab's instrument room is also ready ! Check out the HPLC, Plate Reader for fluorescence/luminescence/absorption and
the Isothermal Calorimeter.
the Isothermal Calorimeter.
02/2017 - The lab's tissue culture room has been fully set up - cannot wait to test the synthesized probes/therapeutics !
02/2017 - The lab's organic synthesis is going full speed !
01/2017 - The lab would like to extend a warm welcome to undergraduate students: Michele Bahtiarian, Omodele Durojaye, Haley L
Wissler, and Hyemi Cho
Wissler, and Hyemi Cho
01/2017 - The lab would like to extend a warm welcome to Dr. Yifu Guan, who has accumulated experience in total synthesis of
natural product and small molecule-based medicinal chemistry.
natural product and small molecule-based medicinal chemistry.
12/2016 - Effective from Dec, 2016, we are proud to be a member of the Fox Chase Cancer Center, Temple's Lewis Katz School
of Medicine
of Medicine
12/2016 - The lab is excited to welcome three new graduate students to the group: Zakey Buuh, Zhigang Lyu, and Di Wang.
Welcome aboard !!
Welcome aboard !!
10/2016 - Effective from Oct, 2016, we are proud to be a member of the University of Pennsylvania, Center for Targeted
Therapeutics& Translational Nanomedicine (CT3N)
Therapeutics& Translational Nanomedicine (CT3N)
09/2016 - Please check out Ross's most recent paper on Proc. Natl. Acad. Sci. U.S.A. ! Some of our current projects are like this -
organic synthesis is not necessarily needed for your play with biology. 08/2016 - Ross has been invited to attend the Cottrell Scholars' New Faculty Workshop in Washington, DC.
07/2016 - We have openings for two postdoctoral research fellows, multiple graduate students and undergraduate students. See
the "Positions Available" page for more details. 07/2016 - The Wang Group opens !
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